Tori Spelling (Donna Martin, Seasons 1-10)
Jennie Garth (Kelly Taylor, Seasons 1-10)
Gabrielle Carteris (Andrea Zuckerman, Seasons 1-5 (Guest 6, 8, 10)
Luke Perry (Dylan McKay, Seasons 1-6, 10)
Tiffani Thiessen (Valerie Malone, Seasons 5-9 (Guest 10)
Shannen Doherty (Brenda Walsh, Seasons 1-4)
Jason Priestley (Brandon Walsh, Seasons 1-9 (Guest 10)
Ian Ziering (Steve Sanders, Seasons 1-10)
Brian Austin Green (David Silver, Seasons 1-10)
Carol Potter (Cindy Walsh, Seasons 1-5 (Guest 6,8)
Kathleen Robertson (Clare Arnold, Seasons 4-7)